Ozone Therapy
Six specialized ozone treatment modalities — from Major Autohemotherapy to Prolozone injections — each tailored to your condition and recovery goals.
Schedule a ConsultationWhat Is Ozone Therapy?
Ozone therapy is one of the most versatile regenerative treatments offered at Glory Regenerative Center. Medical-grade ozone (O₃) stimulates healing, reduces inflammation, fights infection, and improves oxygen delivery to damaged tissues. Dr. Ikudayisi offers six distinct ozone treatment modalities: Major Autohemotherapy (MAH), Prolozone Therapy, Ozonated Saline IV Drip, and targeted Insufflation therapies (rectal, bladder, and sinus). Each modality is selected based on your specific condition — whether you’re treating chronic joint pain, infectious diseases, autoimmune conditions, circulatory disorders, or chronic fatigue. With decades of clinical use worldwide, ozone therapy is a safe and well-established complement to our regenerative medicine protocols.

Benefits
- Stimulates growth factor release and accelerates tissue repair
- Powerful anti-inflammatory and immune-modulating effects
- Enhances oxygen delivery to tissues and improves circulation
- Activates the body’s antioxidant defense systems
- Effective against chronic infections and autoimmune conditions
- Multiple delivery methods tailored to your specific condition
- Can be combined with PRP, prolotherapy, and other regenerative therapies
- Safe, well-established medical therapy with decades of clinical research
Conditions Treated with Ozone Therapy
At Glory Regenerative Center, our physicians administer Ozone Therapy with precision, supporting patients dealing with a wide range of conditions:
- Chronic pain and inflammation
- Joint and musculoskeletal issues
- Chronic infections
- Autoimmune disorders
- Chronic fatigue syndrome
- Viral conditions
- Circulatory disorders
- Neuropathy and nerve-related pain
- Gut and immune health concerns
- Geriatric and age-related decline
Ozone Therapy is offered as part of a personalized regenerative care plan — not as a stand-alone cure. Dr. Ikudayisi will determine whether it is appropriate for your specific condition during your consultation.
Treatment Options at Glory Regenerative
We offer Florida patients several physician-selected ozone modalities. Each is safe, well-established, and chosen based on a comprehensive medical evaluation of your unique case.
Major Autohemotherapy (MAH)
MAH is a cornerstone of Ozone Therapy. A small amount of the patient’s blood is withdrawn, mixed with a precise concentration of medical-grade ozone, and reintroduced into the bloodstream. This process supports the oxygen-carrying capacity of red blood cells, modulates the immune system, and promotes detoxification — making it a valuable therapy for a wide range of conditions.
Prolozone Therapy
For patients seeking relief from musculoskeletal issues, Prolozone Therapy offers a targeted solution. Ozone and nutrients are injected into joints, ligaments, and soft tissues to stimulate regeneration and reduce inflammation — particularly effective for chronic joint pain, joint instability, and musculoskeletal injuries.
Ozonated Saline Drip
The Ozonated Saline Drip infuses a sterile saline solution with ozone, then delivers it intravenously. As the ozonated saline circulates, it supports oxygenation, circulation, detoxification, and immune function — a gentle, well-tolerated systemic option for patients seeking a holistic approach to wellness.
Subcutaneous Ozone
A localized modality in which small amounts of medical-grade ozone are introduced just beneath the skin in selected areas. Used in carefully chosen cases to support circulation, soft-tissue recovery, and localized inflammation control — always under physician guidance and only when clinically appropriate.
Rectal Insufflation
Rectal Insufflation is a non-invasive ozone delivery method that supports systemic oxygenation and immune function, promotes detoxification, and helps support overall gut health. It is comfortable, well-tolerated, and frequently used as part of a broader systemic ozone protocol.
Bladder Insufflation
For targeted urinary wellness, Bladder Insufflation is a minimally invasive procedure that delivers ozone directly into the bladder. It can support patients dealing with recurrent bladder inflammation, interstitial cystitis, and other urinary concerns — with each protocol customized to the individual.
Sinus Insufflation
Sinus Insufflation delivers ozone directly into the sinus passages to help relieve symptoms of chronic sinus infections, nasal congestion, and seasonal allergies. It supports sinus drainage, reduces inflammation, and enhances overall respiratory wellness.
Who Is a Good Candidate?
Ozone therapy may benefit patients with chronic joint or musculoskeletal pain, inflammatory or autoimmune conditions, chronic infections, circulatory disorders, chronic fatigue syndrome, fibromyalgia, neuropathy, or patients seeking to enhance their body’s natural healing and immune response.
How It Works
Medical Evaluation
Dr. Ikudayisi evaluates your condition, medical history, and treatment goals to determine which ozone modality — or combination of modalities — will deliver the best results.
Treatment Preparation
Medical-grade ozone is generated on-site at precise therapeutic concentrations using certified ozone generators.
Ozone Administration
Depending on your protocol, ozone is delivered via Prolozone injection into joints, Major Autohemotherapy (blood draw, ozone mixing, reinfusion), ozonated saline IV drip, subcutaneous ozone in selected localized areas, or targeted insufflation.
Recovery & Follow-Up
Most ozone treatments require no downtime. You can typically resume normal activities immediately. A series of 4–8 sessions is usually recommended for optimal results.
What to Expect
Ozone therapy sessions typically take 30–60 minutes depending on the delivery method. For Prolozone injections, you may experience mild soreness at the injection site for 1–2 days. For Major Autohemotherapy, a small amount of blood is drawn, mixed with medical-grade ozone, and reinfused — the process is comfortable and well-tolerated. Most patients notice meaningful improvement after 2–4 sessions, with cumulative benefits building over the full treatment course.
Available At
Visit Us In Person
8019 N. Himes Ave., Suite 200
Tampa, FL 33614
1818 Harden Blvd., Suite 110
Lakeland, FL 33803
5622 Marine Parkway, Suite 8
New Port Richey, FL 34652
See Real Patient Results
Explore before-and-after photos and patient stories from our ozone therapy patients.


Keloid scar reduction following targeted ozone therapy — visible decrease in size, elevation, and discoloration after treatment.
“Patient testimonials for Ozone Therapy are being collected. Check back soon.”
Patient
Frequently Asked Questions
Why Choose Glory Regenerative for Ozone Therapy?
At Glory Regenerative Center, we prioritize personalized, patient-centered care. Our team is dedicated to guiding you through your wellness journey — ensuring you receive the ozone modality, or combination of modalities, best suited to your unique needs.
From Major Autohemotherapy and Prolozone Therapy to ozonated saline and targeted insufflation, our comprehensive ozone offerings are designed to fit within a broader regenerative care plan. Each protocol is delivered under direct physician oversight, in a calm clinical environment, by a team committed to clinical excellence.
To learn more about our Ozone Therapy options and to work with a leading regenerative medicine physician in Florida, please call today to schedule your consultation.
Related Services
PRP Therapy
Concentrate your body’s own growth factors to accelerate tissue repair, reduce inflammation, and support healing across multiple treatment areas.
Learn MoreMajor Autohemotherapy (MAH)
A physician-led ozone blood therapy that draws a small amount of your blood, enriches it with medical-grade ozone, and reintroduces it to support immune function, circulation, and vitality.
Learn MoreIV Therapy
Physician-formulated IV infusions that deliver vitamins, minerals, and nutrients directly into your bloodstream for 100% absorption and immediate results.
Learn MoreProlotherapy
Dextrose-based regenerative injections that strengthen weakened ligaments, tendons, and joints — treating conditions from chronic back pain to plantar fasciitis without surgery.
Learn MoreProlozone Therapy
Ozone and oxygen injections that reduce inflammation and stimulate tissue repair — treating joint pain, sports injuries, arthritis, and 15+ chronic conditions.
Learn MoreDiscover the Healing Power of Ozone
Schedule a consultation to explore which ozone therapy modality is right for your condition — from Prolozone to Major Autohemotherapy.